Something I find incredibly cool is that they’ve found neandertal bone tools made from polished rib bones, and they couldn’t figure out what they were for for the life of them.
“Wait you’re still using the exact same fucking thing 50,000 years later???”
“Well, yeah. We’ve tried other things. Metal scratches up and damages the hide. Wood splinters and wears out. Bone lasts forever and gives the best polish. There are new, cheaper plastic ones, but they crack and break after a couple years. A bone polisher is nearly indestructible, and only gets better with age. The more you use a bone polisher the better it works.”
It’s just.
50,000 years. 50,000. And over that huge arc of time, we’ve been quietly using the exact same thing, unchanged, because we simply haven’t found anything better to do the job.
i also like that this is a “ask craftspeople” thing, it reminds me of when art historians were all “the fuck” about someone’s ear “deformity” in a portrait and couldn’t work out what the symbolism was until someone who’d also worked as a piercer was like “uhm, he’s fucked up a piercing there”. interdisciplinary shit also needs to include non-academic approaches because crafts & trades people know shit ok
Don’t repost phone numbers and addresses of ICE agents and Nazis unless you really fucking trust the source of the information. It would be so easy for me to put the number of someone I don’t like in a tweet screenshot saying it’s a local ICE director
I don’t get why people hate immigrants so much… Like they’re literally just… People… From another location….
My partner is an immigrant from the UK and still holds his citizenship. At a recent event, an acquaintance talked about how many “immigrants” get jobs over “Canadians” and they shouldn’t allowed to be management (which my partner is). My partner reaches across the table and goes “Hi, immigrant here!” and she goes “Oh I didn’t mean immigrants like you…” And you can so tell they just mean “brown people” or “Asian people” but they pretend it’s about jobs and shit.
That’s the same with my family. We were war immigrants from the soviet union and now live in Germany. Now the syrians are here because they also have war, and people keep asking me why I’m defending them so mercilessly. And when I tell them that my family (that is still alive) has gone through the same bullshit. But they insist that both scenarios are completely different. They’re not different, you’re just racist.
So with all the ish that Edward Elric goes through, did anyone else realize that a rock
is the thing that leaves a scar
FOR 21 EPISODES.
That’s a third of the series. For a third of the series- with every fight and battle that the Fullmetal Alchemist is in, it’s a ROCK that marks him for a third of the series.
Actually !! The scar that ed has during the rest of the series isn’t from a rock. He first gets it in his fight with the Slicer brothers in Episode 8:
and then we see him bleeding on his forehead:
Episode 9 we see him with the bandages:
Episode 10 when travelling to Rush Valley and Dublith, the bandages are gone:
AND THEN in episode 13 we see him reopen it in his fight with Greed:
More bandages in Episode 14 and 15:
episode 16 - 20 no bandages:
and then in episode 21 he reopens the scar AGAIN when the rock hits him
episode 22:
again with them bandages: episode 23 - 31
episode 32 he has the scar now:
and then its finally healed in episode 44!!
it healed along with his wound from getting impaled
both brotherhood and arakawa are amazing at adding in details like this its amazing tbh
pro tip: just bc someone has good takes in one area doesnt mean its all good everywhere and it certainly doesnt mean they havent internalized any harmful shit, so dont just assume somebody’s sex politics r good and healthy bc u like their disability politics or whatever
man tumblr discourse is so performative and exhausting. thinking pansexuality is transphobic just means you don’t know what pansexuality even is. how can y’all confidently argue about things you clearly don’t know jack shit about. go outside.
while i’m at it, if you pretend like you’re against cringe culture, then reblog posts that are just “Oh Fuck Cringe Ace People Fail” (usually fake, overblown, or just a silly post by a kid) then you’re also performative.
so uhhhhhh i know this is a plant blog but realtalk lads im a little freaked out by that wild ass new organ discovered in our bodies according to a paper published literally yesterday am i right my lads, my bois, lmao hhaha
(as of 3/28/2018, paper was published in the reputable international research journal “Nature” on 3/27/2018, publication here, study was started in 2013) ok so like uhhh this is my rough translation of the paper they published using my current level of biological knowledge, if anyone else has a more in depth understanding with human anatomy things and would like to add on with anything i might have missed feel free to add but this is my takeaway:
-scientists were looking at some stuff in the inside of a bile duct they were studying in a live patient (this will be important later) using a laser that lets them see the cells in real time. they injected some stuff into the duct and saw the spaces inbetween the cells fill up with fluid in strange, tube-like structures that didn’t correspond with what they expected to be there, so they sectioned and froze them to study them closer; they realized that upon closer inspection, the fluid-filled places were VERY small collagen tubes forming a complex matrix of bundles surrounded by a weird cell covering that seemed to connect them to one another. they called this the Interstitium.
-they sectioned some more places where squeezy things might happen, like the inner linings of the bladder, lungs, lymph nodes, and the soft tissue enclosing our muscles, filled them with the same indicator, and hyper froze them like they did to the first sample and found the same weird matrix of fluid-filled tubing:
they concluded from what they found from this that:
1. our previous thought of the space inbetween the cells in these parts of the body, which we thought were just kinda like, there or whatever doing nothing (a series of spaces that were already called the Interstitium that were largely ignored), are actually full of complex tubing running through a ton of very important parts of your body
2. when the structures they’re chilling around (like your bladder and bowel) contract, the fluid moves around all weird
3. the reason this wasn’t discovered before is because when the tubes are squished too hard- like when scientists are cutting into them- they have a tendency to collapse really easily,especially when being treated with chemicals for microscope use, giving the impression of the kind of tissues that we’ve traditionally seen in specimens and thought of being in these sensitive areas (closely compact and dense cell mats). it turns out that in living people, these tubes run between the cells carrying fluid; the scientists were able to see this initially in live patients using the above mentioned laser technology, and then took live biopsies by quickly freezing the cells in place before removal to prevent their collapse.
4. yes, these can move cancer cells around, which is HUGE seeing as they seem to enclose a LOT of important and delicate muscles in our bodies in one giant, complex system. when they looked at it in cancer patients, the tumors they found seemed to kind of be….leaking….into them…..because the tumors were putting pressure on the fluid tubes….which easily collapse…..and move things that fall into the fluid around….
5. the scientists also explored things like hernias and colon damage in relation to these, but unfortunately this is where my translation powers run out as non-plant-related terminology starts being used lmao im so sorry im like this
tl;dr: the membranes that surround some really important parts of squishy things like our stomach, bowels, colon, lungs, muscles, etc are full of very delicate and complex tubing that runs in a weirdly complex system to other important squishy things throughout our bodies and looks like a weird organ that we didn’t know was there before (or like, we knew about it, we just didn’t know it was so…connected and uh…organy). also it seems to have an impact on the spread of cancer throughout these regions
Graduate of Biomedical Science here; this paper is pretty much understandable to me.
You’ve picked out the main stuff, but here’s some things I think is very interesting:
The discovery of these spaces dramatically expands the lymphatic system. Basically, this is how the lymph nodes are connected to the rest of the body. Before it was kinda like ‘yeah here are the lymph nodes, and the lymph fluid kinda goes to the somehow? idk’. But now we have a whole system. It’s like discovering the entire circulatory system when before you only had the heart to work with.
This is super important for cancers and detecting when a cancer has spread (metastasised, in the lingo). They talk about the spread of cancers into the deeper tissues (such as stomach cancers invading their submucosal tissue and skin cancers pentrating deeper into the dermis layers), but what is most important is that they detected the cancers spreading into the interstitial spaces before there was anything to detect within the lymph nodes. This is super important, as usually lymph node biopsies are done to detect if a cancer is spreading; this is before that very stage. This is literally catching cancers in the act of spreading before they’ve hit another organ this is fucking incredible.
It’s providing an explanation for oedema (or edema, for my US followers), which is the build-up of fluid in certain areas of the body (usually the lower limbs, but it can be anywhere). For so long it’s been like ‘I guess there’s something wrong with your blood vessels??’ but like the lymphatic system, we’ve now got another explanation. ‘Ah, okay, there’s something going down in your interstitial fluid!’ A more effective diagnosis and treatment could be made, Bam! Enrich more people’s lives.
They may play a role in how scar formation works. Some scar tissue can get a bit crazy and grow too much, meaning it needs to be cut away as it hinders movement or it just fucking painful. Perhaps the interstitial tubing/fluid plays a role in this, considering collagen is used in scar tissue, and these spaces are full of it.
There’s clearly communication between these spaces and the digestive system, as they found tattoo pigment from the intestines in these spaces. Tattooing in the intestine is done to mark lesions for removal or observation later on, so the fact this pigment is actively moving out of the digestive system and else means it could play a role in disease we don’t know much about, like inflammatory bowel conditions.
Basically, THIS IS FUCKING HUGE AND COULD POTENTIALLY CHANGE THE GAME IN A BIG WAY.
Thank you OP for sharing this, I haven’t nerded out and been so fascinated by a study in a long time.
ALSO GOOD ON YOU NATURE FOR MAKING THE FULL ARTICLE FREE. HONOUR ON YOU AND YOUR COWS.
Right on.
… so you’re telling me humans basically had an entire second circulatory system we just didn’t know about until now?
my great-grandfather had to leave italy in the 20′s because he hit a fascist with a tuba, so if you think I am going to take this sitting down you are going to have to catch these hands and also this tuba
Fun story my Great Great Grandma left Germany in the 1920s because she had family in the US and could get citizenship pretty easily and once she was over in the US she then smuggled over 15 jewish families out by forging family documents so now my aunts are currently in the process of trying to tell the real ones from the fake ones because my great gran just died and there are legally over 100 surviving descendants but we know that math is a lil screwy.
Sometimes a family is you, your kids, your grandkids, your great grandkids, and the 15 Jewish families you helped smuggle out of Nazi Germany.